Error: "Your computer's Trusted Platform Module has malfunctioned" when opening a Microsoft Office application in Windows 10


Symptoms

You receive the following error when attempting to open a Microsoft Office application:

Something went wrong. Your computer's Trusted Platform Module has malfuctioned. If this error persists, contact your system administrator with the error code 80284001.

example screenshot

Cause

Unknown

Resolution

Disable startup programs and restart your computer. You can attempt to enable your preferred programs one by one and restart to see which one might be causing the error to occur.