Symptoms
After installing Microsoft Defender for Endpoint on your Mac, you notice the following message in System Preferences > Security & Privacy:
Some system software requires your attention before it can be used.
Cause
Apple requires that all new system extensions being installed from third-party developers in macOS be manually allowed.
Resolution
- In the bottom left-hand corner, click the lock icon.
- Authenticate using Touch ID or the username and password of an administrator on your Mac.
- Click Details.
- Check the box(es) next to "Microsoft Defender ATP.app". Then, click OK.
- Close System Preferences.
Outcome
The message in System Preferences will be gone and Microsoft Defender for Endpoint will function as expected on your Mac.